Search on: P21-ACTIVATED KINASES 
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Descriptor English:   p21-Activated Kinases 
Descriptor Spanish:   Quinasas p21 Activadas 
Descriptor Portuguese:   Quinases Ativadas por p21 
Tree Number:   D08.811.913.696.620.682.700.596
D12.644.360.552
D12.776.476.548
Definition English:   A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEIN. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52745 
Unique Identifier:   D054462 

Occurrence in VHL: 		 

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